Deoxyguanosine Kinase Antikörper (AA 76-277) (APC)

Produktnummer ABIN7984861

Der Kaninchen Polyklonal anti-Deoxyguanosine Kinase Antikörper wird verwendet zum Nachweis von Deoxyguanosine Kinase in Proben von Human und Maus. Er wurde validiert für FACS.

Kurzübersicht für Deoxyguanosine Kinase Antikörper (AA 76-277) (APC) (ABIN7984861)

Target: Deoxyguanosine Kinase (DGUOK)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Deoxyguanosine Kinase Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Deoxyguanosine Kinase Antikörper (APC)

Bindungsspezifität: AA 76-277

Verwendungszweck: Anti-DGUOK Antibody APC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DGUOK recombinant protein (Position: Q76-L277).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Deoxyguanosine Kinase

Target: Deoxyguanosine Kinase (DGUOK)

Andere Bezeichnung: DGUOK

Hintergrund:

Background: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Gene Full Name: deoxyguanosine kinase

Gen-ID: 1716

UniProt: Q16854

Pathways: Ribonucleoside Biosynthetic Process