Deoxyguanosine Kinase Antikörper (AA 76-277)
Kurzübersicht für Deoxyguanosine Kinase Antikörper (AA 76-277) (ABIN7984853)
Target
Alle Deoxyguanosine Kinase (DGUOK) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 76-277
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Verwendungszweck
- Anti-DGUOK Antibody
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Produktmerkmale
- Anti-DGUOK Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human DGUOK recombinant protein (Position: Q76-L277).
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Isotyp
- IgG
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Applikationshinweise
- Western blot, 0.25-0.5 μg/mL, Human, Mouse Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing. -
Haltbarkeit
- 12 months
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- Deoxyguanosine Kinase (DGUOK)
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Andere Bezeichnung
- DGUOK
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Hintergrund
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Background: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
Gene Full Name: deoxyguanosine kinase
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Molekulargewicht
- 28 kDa
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Gen-ID
- 1716
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UniProt
- Q16854
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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