DDHD1 Antikörper (AA 63-711) (FITC)

Produktnummer ABIN7983943

Der Kaninchen Polyklonal anti-DDHD1 Antikörper wird verwendet zum Nachweis von DDHD1 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für DDHD1 Antikörper (AA 63-711) (FITC) (ABIN7983943)

Target: DDHD1 (DDHD Domain Containing 1 (DDHD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDHD1 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-DDHD1 Antikörper (FITC)

Bindungsspezifität: AA 63-711

Verwendungszweck: Anti-DDHD1 Antibody FITC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human DDHD1 recombinant protein (Position: P63-S711).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu DDHD1

Target: DDHD1 (DDHD Domain Containing 1 (DDHD1))

Andere Bezeichnung: DDHD1

Hintergrund:

Background: This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: DDHD domain containing 1

Gen-ID: 80821

UniProt: Q8NEL9