CST3 Antikörper (AA 31-146) (Cy3)

Produktnummer ABIN7982749

Der Maus Monoklonal anti-CST3 Antikörper wird verwendet zum Nachweis von CST3 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für CST3 Antikörper (AA 31-146) (Cy3) (ABIN7982749)

Target: CST3 (Cystatin C (CST3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CST3 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Klon: 8H7

Produktdetails anti-CST3 Antikörper (Cy3)

Bindungsspezifität: AA 31-146

Verwendungszweck: Anti-Cystatin C/CST3 Antibody (monoclonal, 8H7) Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Cystatin C recombinant protein (Position: K31-A146).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu CST3

Target: CST3 (Cystatin C (CST3))

Andere Bezeichnung: CST3

Hintergrund:

Background: Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

Gene Full Name: cystatin C

Gen-ID: 1471

UniProt: P01034