CST3 Antikörper (AA 31-146) (APC)

Produktnummer ABIN7982744

Der APC-konjugierte Maus Monoklonal anti-CST3 Antikörper (Klon 4H8) (ABIN7982744) detektiert spezifisch CST3 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CST3 Antikörper (AA 31-146) (APC) (ABIN7982744)

Target: CST3 (Cystatin C (CST3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CST3 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: 4H8

Produktdetails anti-CST3 Antikörper (APC)

Bindungsspezifität: AA 31-146

Verwendungszweck: Anti-Cystatin C/CST3 Antibody (monoclonal, 4H8) APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Cystatin C recombinant protein (Position: K31-A146).

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu CST3

Target: CST3 (Cystatin C (CST3))

Andere Bezeichnung: CST3

Hintergrund:

Background: Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

Gene Full Name: cystatin C

Gen-ID: 1471

UniProt: P01034