PPIB Antikörper (C-Term) (Fluoro488)

Produktnummer ABIN7982563

Der Kaninchen Polyklonal anti-PPIB Antikörper wird verwendet zum Nachweis von PPIB in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für PPIB Antikörper (C-Term) (Fluoro488) (ABIN7982563)

Target: PPIB (Cyclophilin B (PPIB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPIB Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PPIB Antikörper (Fluoro488)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Cyclophilin B/PPIB Antibody Fluoro488 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by one amino acid,and from the related rat sequence by two amino acids.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Cyclophilin B, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PPIB

Target: PPIB (Cyclophilin B (PPIB))

Andere Bezeichnung: PPIB

Hintergrund:

Background: Peptidyl-prolyl cis-trans isomerase B, also known as CYPB, is an enzyme that in humans is encoded by the PPIB gene. This gene is mapped to 15q22.31. The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.

Gene Full Name: peptidylprolyl isomerase B

Sequence Similarities: Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.

Gen-ID: 5479

UniProt: P23284