CD207 Antikörper (AA 161-260) (Biotin)
Kurzübersicht für CD207 Antikörper (AA 161-260) (Biotin) (ABIN748570)
Target
Alle CD207 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 161-260
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Kreuzreaktivität
- Maus
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Homologie
- Human,Rat
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human CD207
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Isotyp
- IgG
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Applikationshinweise
- WB 1:300-5000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- CD207 (CD207 Molecule, Langerin (CD207))
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Andere Bezeichnung
- Langerin/CD207
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Hintergrund
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Synonyms: CLEC4K, C-type lectin domain family 4 member K, Langerin, CD207
Background: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs), is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
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Gen-ID
- 50489
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UniProt
- Q9UJ71
Target
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