COBRA1 Antikörper (AA 1-252)

Produktnummer ABIN7980851

Der Kaninchen Polyklonal anti-COBRA1 Antikörper (ABIN7980851) detektiert spezifisch COBRA1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für COBRA1 Antikörper (AA 1-252) (ABIN7980851)

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COBRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Carrier-free

Produktdetails anti-COBRA1 Antikörper

Bindungsspezifität: AA 1-252

Verwendungszweck: Anti-COBRA1/NELFB Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-COBRA1/NELFB Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human COBRA1 recombinant protein (Position: M1-E252).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu COBRA1

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Andere Bezeichnung: NELFB

Hintergrund:

Background: Cofactor of BRCA1, also known as COBRA1, is a human gene that encodes NELF-B. NELF-B is a subunit of negative elongation factor (NELF), which also includes NELF-A (WHSC2), either NELF-C or NELF-D (TH1L), and NELF-E (RDBP). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1) and SPT5 (SUPT5H), to cause transcriptional pausing of RNA polymerase II. COBRA1 was initially identified in a yeast two-hybrid screen using the BRCT1 domain of BRCA1 as bait.

Gene Full Name: negative elongation factor complex member B

Molekulargewicht: 66 kDa

Gen-ID: 25920

UniProt: Q8WX92