PGE2 Antikörper (AA 281-384)

Produktnummer ABIN748403

Der Kaninchen Polyklonal Anti-PGE2 Antikörper wurde für ELISA, IHC (fro), FACS, IF (cc), IF (p) und IHC (p) validiert. Er ist geeignet, PGE2 in Proben von Human, Maus und Ratte zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für PGE2 Antikörper (AA 281-384) (ABIN748403)

Target: PGE2 (Prostaglandin E2 (PGE2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGE2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PGE2 Antikörper

Bindungsspezifität: AA 281-384

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse PGES2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-PGE2 Antikörper (ABIN748403)

Manaserh, Chikkamenahalli, Ravi, Dube, Park, Hill: "Ablating astrocyte insulin receptors leads to delayed puberty and hypogonadism in mice." in: PLoS biology, Vol. 17, Issue 3, pp. e3000189, (2019) (PubMed).

Chia, Liu, Feng, Tseng, Hung, Chen, Tan: "The Antinociceptive Effect of Light-Emitting Diode Irradiation on Incised Wounds Is Correlated with Changes in Cyclooxygenase 2 Activity, Prostaglandin E2, and Proinflammatory Cytokines." in: Pain research & management, Vol. 2017, pp. 4792489, (2017) (PubMed).

Liu, Li, Liu, She, Shi, Li, Wang, Jiang: "Activated hepatic stellate cells directly induce pathogenic Th17 cells in chronic hepatitis B virus infection." in: Experimental cell research, Vol. 359, Issue 1, pp. 129-137, (2017) (PubMed).

de Jesus, Spadacci-Morena, dos Anjos Rabelo, Pinfildi, Fukuda, Plapler: "Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon." in: Lasers in medical science, Vol. 30, Issue 1, pp. 153-8, (2015) (PubMed).

Details zu PGE2

Target: PGE2 (Prostaglandin E2 (PGE2))

Hintergrund:

Synonyms: Gbf1, Pges2, C79137, Mpges2, 6138H1Rik, Prostaglandin E synthase 2, GATE-binding factor 1, GBF-1, Microsomal prostaglandin E synthase 2, mPGES-2, Ptges2,

Background: Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (By similarity). May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB, however, the relevance of transcription activation activity remains unclear.

Gen-ID: 96979

UniProt: Q8BWM0