PGE2 Antikörper (AA 281-384)

Produktnummer ABIN748403

Der Kaninchen Polyklonal Anti-PGE2-Antikörper wurde für FACS, IF (cc), IF (p), ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, PGE2 in Proben von Human, Maus und Ratte zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für PGE2 Antikörper (AA 281-384) (ABIN748403)

Target: PGE2 (Prostaglandin E2 (PGE2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGE2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PGE2 Antikörper

Bindungsspezifität: AA 281-384

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse PGES2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-PGE2 Antikörper (ABIN748403)

Manaserh, Chikkamenahalli, Ravi, Dube, Park, Hill: "Ablating astrocyte insulin receptors leads to delayed puberty and hypogonadism in mice." in: PLoS biology, Vol. 17, Issue 3, pp. e3000189, (2019) (PubMed).

Chia, Liu, Feng, Tseng, Hung, Chen, Tan: "The Antinociceptive Effect of Light-Emitting Diode Irradiation on Incised Wounds Is Correlated with Changes in Cyclooxygenase 2 Activity, Prostaglandin E2, and Proinflammatory Cytokines." in: Pain research & management, Vol. 2017, pp. 4792489, (2017) (PubMed).

Liu, Li, Liu, She, Shi, Li, Wang, Jiang: "Activated hepatic stellate cells directly induce pathogenic Th17 cells in chronic hepatitis B virus infection." in: Experimental cell research, Vol. 359, Issue 1, pp. 129-137, (2017) (PubMed).

de Jesus, Spadacci-Morena, dos Anjos Rabelo, Pinfildi, Fukuda, Plapler: "Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon." in: Lasers in medical science, Vol. 30, Issue 1, pp. 153-8, (2015) (PubMed).

Details zu PGE2

Target: PGE2 (Prostaglandin E2 (PGE2))

Hintergrund:

Synonyms: Gbf1, Pges2, C79137, Mpges2, 6138H1Rik, Prostaglandin E synthase 2, GATE-binding factor 1, GBF-1, Microsomal prostaglandin E synthase 2, mPGES-2, Ptges2,

Background: Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (By similarity). May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB, however, the relevance of transcription activation activity remains unclear.

Gen-ID: 96979

UniProt: Q8BWM0