Claudin 3 Antikörper (AA 101-220)

Produktnummer ABIN7980488

Der Maus Monoklonal anti-Claudin 3 Antikörper (Klon 4C7D2) (ABIN7980488) detektiert spezifisch Claudin 3 in WB, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Claudin 3 Antikörper (AA 101-220) (ABIN7980488)

Target: Claudin 3 (CLDN3)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Claudin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Güteklasse: Carrier-free

Klon: 4C7D2

Produktdetails anti-Claudin 3 Antikörper

Bindungsspezifität: AA 101-220

Verwendungszweck: Anti-Claudin 3/CLDN3 Antibody (monoclonal, 4C7D2)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Claudin 3/CLDN3 Antibody.(monoclonal, 4C7D2)-2. Tested in IF, IHC, WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Claudin 3/CLDN3 recombinant protein (Position: A101-V220).

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Claudin 3

Target: Claudin 3 (CLDN3)

Andere Bezeichnung: CLDN3

Hintergrund:

Background: Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Gene Full Name: claudin 3

Molekulargewicht: 20 kDa

Gen-ID: 1365

UniProt: O15551

Pathways: Hepatitis C