C10orf2 Antikörper (AA 39-635) (Fluoro550)

Produktnummer ABIN7979974

Der Kaninchen Polyklonal anti-C10orf2 Antikörper wird verwendet zum Nachweis von C10orf2 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für C10orf2 Antikörper (AA 39-635) (Fluoro550) (ABIN7979974)

Target: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C10orf2 Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-C10orf2 Antikörper (Fluoro550)

Bindungsspezifität: AA 39-635

Verwendungszweck: Anti-Twinkle/TWNK Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Twinkle,TWNK shares 87.8% amino acid (aa) sequence identity with mouse Twinkle,TWNK.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Twinkle/TWNK recombinant protein (Position: R39-K635). Human Twinkle/TWNK shares 87.8% amino acid (aa) sequence identity with mouse Twinkle/TWNK.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu C10orf2

Target: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Andere Bezeichnung: TWNK

Hintergrund:

Background: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: twinkle mtDNA helicase

Gen-ID: 56652

UniProt: Q96RR1