Chp2 Antikörper (AA 1-196) (HRP)

Produktnummer ABIN7979713

Der Kaninchen Polyklonal anti-Chp2 Antikörper wird verwendet zum Nachweis von Chp2 in Proben von Human. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für Chp2 Antikörper (AA 1-196) (HRP) (ABIN7979713)

Target: Chp2

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Chp2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Chp2 Antikörper (HRP)

Bindungsspezifität: AA 1-196

Verwendungszweck: Anti-CHP2 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human CHP2 shares 81.6% amino acid (aa) sequence identity with both mouse,rat CHP2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CHP2 recombinant protein (Position: M1-K196). Human CHP2 shares 81.6% amino acid (aa) sequence identity with both mouse and rat CHP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Chp2

Target: Chp2

Hintergrund:

Background: This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520.

Gene Full Name: calcineurin like EF-hand protein 2

Gen-ID: 63928

UniProt: O43745