CXCR4 Antikörper (AA 19-334) (FITC)
Kurzübersicht für CXCR4 Antikörper (AA 19-334) (FITC) (ABIN7979349)
Target
Alle CXCR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 19-334
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Verwendungszweck
- Anti-CXCR4 Antibody FITC Conjugated
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human CXCR4 recombinant protein (Position: G19-R334).
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Andere Bezeichnung
- CXCR4
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Hintergrund
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Background: CXCR4 (Chemokine,CXC Motif, Receptor 4), also known as FUSIN or NPY3R, is a protein that in humans is encoded by the CXCR4 gene. It is the receptor for the CXC chemokine SDF1 that has essential functions on embryo organogenesis, immunological functions and T lymphocyte trafficking. CXCR4 is the only SDF1 receptor identified so far. This suggests that CXCR4 expression is critical for the biological effects of SDF1. CXCR4 is also a seven-transmembrane-spanning, G-protein-coupled receptor for the CXC chemokine PBSF/SDF-1. It functions as a co-receptor for T-cell-line tropic human immunodeficiency virus HIV-1. It was concluded that PBSF/SDF-1 and CXCR4 define a new signalling system for organ vascularization.
Gene Full Name: C-X-C motif chemokine receptor 4
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Gen-ID
- 7852
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UniProt
- P61073
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Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
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