CXCL5 Antikörper (AA 38-130) (Fluoro488)

Produktnummer ABIN7979236

Der Kaninchen Polyklonal anti-CXCL5 Antikörper wird verwendet zum Nachweis von CXCL5 in Proben von Ratte. Er wurde validiert für FACS.

Kurzübersicht für CXCL5 Antikörper (AA 38-130) (Fluoro488) (ABIN7979236)

Target: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL5 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CXCL5 Antikörper (Fluoro488)

Bindungsspezifität: AA 38-130

Verwendungszweck: Anti-CXCL5 Antibody Fluoro488 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: coli-derived rat CXCL5 recombinant protein (Position: A38-Q130). Rat CXCL5 shares 58.7%,76.3% amino acid (aa) sequence identity with human,mouse CXCL5,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived rat CXCL5 recombinant protein (Position: A38-Q130). Rat CXCL5 shares 58.7% and 76.3% amino acid (aa) sequence identity with human and mouse CXCL5, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu CXCL5

Target: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Andere Bezeichnung: Cxcl5

Hintergrund:

Background: C-X-C motif chemokine 5?or ENA-78 is a?protein?that in humans is encoded by the?CXCL5?gene. The protein encoded by this gene, CXCL5 is a small?cytokine?belonging to the CXC?chemokine?family. It is produced following stimulation of cells with the inflammatory cytokines?interleukin-1?or?tumor necrosis factor-alpha.?Expression of CXCL5 has also been observed ineosinophils, and can be inhibited with the type II?interferon?IFN-γ. This chemokine stimulates the chemotaxis of neutrophils possessing?angiogenic?properties. It elicits these effects by interacting with the cell surface?chemokine receptor?CXCR2.?The?gene?for CXCL5 is encoded on four?exons?and is located on human?chromosome 4?amongst several other CXC chemokine genes.?CXCL5 has been implicated in connective tissue remodelling.?Also, CXCL5 has been described to regulate neutrophil homeostasis.

Gene Full Name: C-X-C motif chemokine ligand 6

Gen-ID: 105988538

UniProt: P97885

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity