CNOT7 Antikörper (AA 3-285) (APC)

Produktnummer ABIN7976148

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CNOT7 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CNOT7 Antikörper (AA 3-285) (APC) (ABIN7976148)

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT7 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CNOT7 Antikörper (APC)

Bindungsspezifität: AA 3-285

Verwendungszweck: Anti-CNOT7 Antibody APC Conjugated

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CNOT7 recombinant protein (Position: A3-S285).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu CNOT7

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Andere Bezeichnung: CNOT7

Hintergrund:

Background: CCR4-NOT transcription complex subunit 7 is a protein that in humans is encoded by the CNOT7 gene. The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

Gene Full Name: CCR4-NOT transcription complex subunit 7

Gen-ID: 29883

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization