Calpain 6 Antikörper (AA 1-641) (Biotin)

Produktnummer ABIN7974380

Der Biotin-konjugierte Kaninchen Polyklonal anti-Calpain 6 Antikörper (ABIN7974380) detektiert spezifisch Calpain 6 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Calpain 6 Antikörper (AA 1-641) (Biotin) (ABIN7974380)

Target: Calpain 6 (CAPN6)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calpain 6 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Calpain 6 Antikörper (Biotin)

Bindungsspezifität: AA 1-641

Verwendungszweck: Anti-Calpain 6/CAPN6 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Calpain 6,CAPN6 shares 95.2%,95% amino acid (aa) sequence identity with mouse,rat Calpain 6,CAPN6,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Calpain 6/CAPN6 recombinant protein (Position: M1-L641). Human Calpain 6/CAPN6 shares 95.2% and 95% amino acid (aa) sequence identity with mouse and rat Calpain 6/CAPN6, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Calpain 6

Target: Calpain 6 (CAPN6)

Andere Bezeichnung: CAPN6

Hintergrund:

Background: Calpain-6 (also known as calpamodulin) is a protein in humans that is encoded by the CAPN6 gene. Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

Gene Full Name: calpain 6

Gen-ID: 827

UniProt: Q9Y6Q1