Calpain 3 Antikörper (AA 42-764) (HRP)

Produktnummer ABIN7974364

Der Kaninchen Polyklonal anti-Calpain 3 Antikörper wird verwendet zum Nachweis von Calpain 3 in Proben von Human und Maus. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für Calpain 3 Antikörper (AA 42-764) (HRP) (ABIN7974364)

Target: Calpain 3 (CAPN3)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calpain 3 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Calpain 3 Antikörper (HRP)

Bindungsspezifität: AA 42-764

Verwendungszweck: Anti-Calpain 3/CAPN3 Antibody HRP Conjugated

Homologie: Human CAPN3 shares 93.5%,94.2% amino acid (aa) sequence identity with mouse,rat CAPN3,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Calpain 3/CAPN3 recombinant protein (Position: I42-D764). Human CAPN3 shares 93.5% and 94.2% amino acid (aa) sequence identity with mouse and rat CAPN3, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Calpain 3

Target: Calpain 3 (CAPN3)

Andere Bezeichnung: Calpain 3/CAPN3

Hintergrund:

Background: Calpain-3 is a protein that in humans is encoded by the CAPN3 gene. Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.

Gene Full Name: calpain 3

Gen-ID: 825

UniProt: P20807

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development