Cadherin 13 Antikörper (AA 149-692) (Fluoro594)

Produktnummer ABIN7973833

Der Kaninchen Polyklonal anti-Cadherin 13 Antikörper wird verwendet zum Nachweis von Cadherin 13 in Proben von Human und Ratte. Er wurde validiert für FACS.

Kurzübersicht für Cadherin 13 Antikörper (AA 149-692) (Fluoro594) (ABIN7973833)

Target: Cadherin 13 (CDH13)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 13 Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Cadherin 13 Antikörper (Fluoro594)

Bindungsspezifität: AA 149-692

Verwendungszweck: Anti-H Cadherin/CDH13 Antibody Fluoro594 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human H Cadherin/CDH13 recombinant protein (Position: E149-A692).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Cadherin 13

Target: Cadherin 13 (CDH13)

Andere Bezeichnung: CDH13

Hintergrund:

Background: T-cadherin also known as cadherin 13, H-cadherin (heart) (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: cadherin 13

Gen-ID: 1012

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization