EZH2 Antikörper (AA 255-350) (HRP)

Produktnummer ABIN747587

Der Kaninchen Polyklonal Anti-EZH2-Antikörper wurde für ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, EZH2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für EZH2 Antikörper (AA 255-350) (HRP) (ABIN747587)

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EZH2 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-EZH2 Antikörper (HRP)

Bindungsspezifität: AA 255-350

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KMT6/EZH2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu EZH2

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Andere Bezeichnung: KMT6

Hintergrund:

Synonyms: Enhancer of zeste homolog 2, Enx1h, MGC9169, Enhancer of zeste 2, ENX-1, ENX 1, ENX1, EZH1, EZH2, EZH 2, EZH2_HUMAN, Histone-lysine N-methyltransferase EZH2, KMT6A, Lysine N-methyltransferase 6, Enhancer of zeste homolog 2 Drosophila, Enhancer of zeste, Drosophila, homolog 2, KMT 6, KMT6, KMT6A, WVS2.

Background: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].

Gen-ID: 2146

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation