BAG2 Antikörper (AA 1-211) (APC)

Produktnummer ABIN7972328

Der APC-konjugierte Maus Monoklonal anti-BAG2 Antikörper (Klon 8F11G2) (ABIN7972328) detektiert spezifisch BAG2 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für BAG2 Antikörper (AA 1-211) (APC) (ABIN7972328)

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BAG2 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: 8F11G2

Produktdetails anti-BAG2 Antikörper (APC)

Bindungsspezifität: AA 1-211

Verwendungszweck: Anti-BAG2 Antibody (monoclonal, 8F11G2) APC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: Human BAG2 shares 93.4% amino acid (aa) sequence identity with mouse BAG2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human BAG2 recombinant protein (Position: M1-N211). Human BAG2 shares 93.4% amino acid (aa) sequence identity with mouse BAG2.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu BAG2

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Andere Bezeichnung: BAG2

Hintergrund:

Background: BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.

Gene Full Name: BAG cochaperone 2

Gen-ID: 9532

UniProt: O95816