CD147 Antikörper (Middle Region) (HRP)

Produktnummer ABIN7972205

Der HRP-konjugierte Kaninchen Polyklonal anti-CD147 Antikörper (ABIN7972205) detektiert spezifisch CD147 in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CD147 Antikörper (Middle Region) (HRP) (ABIN7972205)

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD147 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CD147 Antikörper (HRP)

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-CD147/BSG Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human CD147.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Andere Bezeichnung: BSG

Hintergrund:

Background: Emmprin, extracellular matrix metalloproteinase inducer, also known as Emmprin (BSG) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the Emmprin gene. the BSG gene contains 8 exons and spans 10.8 kb. The human BSG gene is mapped to 19p13.3. This protein is a determinant for the Ok blood group system. Emmprin has been shown to be an essential receptor on red blood cells for the malaria parasite. Emmprin is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, Emmprin is though also to play a role in intercellular recognition. Emmprin also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Emmprin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes.

Gene Full Name: basigin (Ok blood group)

Sequence Similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Gen-ID: 682

UniProt: P35613

Pathways: S100 Proteine