Azurocidin Antikörper (AA 27-245) (Fluoro550)

Produktnummer ABIN7971750

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Azurocidin in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Azurocidin Antikörper (AA 27-245) (Fluoro550) (ABIN7971750)

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Azurocidin Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Azurocidin Antikörper (Fluoro550)

Bindungsspezifität: AA 27-245

Verwendungszweck: Anti-Azurocidin/AZU1 Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Azurocidin/AZU1 recombinant protein (Position: I27-N245).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Azurocidin

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Andere Bezeichnung: AZU1

Hintergrund:

Background: Azurocidin also known as cationic antimicrobial protein CAP37 or heparin-binding protein (HBP) is a protein that in humans is encoded by the AZU1 gene. Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

Gene Full Name: azurocidin 1

Gen-ID: 566

UniProt: P20160