AIRE Antikörper (AA 1-120) (Fluoro488)
Kurzübersicht für AIRE Antikörper (AA 1-120) (Fluoro488) (ABIN7971594)
Target
Alle AIRE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-120
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Verwendungszweck
- Anti-AIRE Antibody Fluoro488 Conjugated
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Homologie
- Human AIRE shares 87.2% amino acid (aa) sequence identity with mouse AIRE.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human AIRE recombinant protein (Position: M1-K120). Human AIRE shares 87.2% amino acid (aa) sequence identity with mouse AIRE.
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- AIRE (Autoimmune Regulator (AIRE))
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Andere Bezeichnung
- AIRE
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Hintergrund
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Background: The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
Gene Full Name: autoimmune regulator
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Gen-ID
- 326
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UniProt
- O43918
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Pathways
- Chromatin Binding
Target
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