ALOX12 Antikörper (C-Term) (PE)

Produktnummer ABIN7969815

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ALOX12 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ALOX12 Antikörper (C-Term) (PE) (ABIN7969815)

Target: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALOX12 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ALOX12 Antikörper (PE)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-12 Lipoxygenase/ALOX12 Antibody PE Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related rat sequence by four amino acids,and from the related mouse sequence by five amino acids.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ALOX12, different from the related rat sequence by four amino acids, and from the related mouse sequence by five amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ALOX12

Target: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Andere Bezeichnung: ALOX12

Hintergrund:

Background: ALOX12, Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNAArachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12 (S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.

Gene Full Name: arachidonate 12-lipoxygenase, 12S type

Sequence Similarities: Belongs to the lipoxygenase family.

Gen-ID: 7314

UniProt: P18054

Pathways: Positive Regulation of Endopeptidase Activity