ANTXR1 Antikörper (AA 33-301) (APC)

Produktnummer ABIN7969121

Der APC-konjugierte Kaninchen Polyklonal anti-ANTXR1 Antikörper (ABIN7969121) detektiert spezifisch ANTXR1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ANTXR1 Antikörper (AA 33-301) (APC) (ABIN7969121)

Target: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANTXR1 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ANTXR1 Antikörper (APC)

Bindungsspezifität: AA 33-301

Verwendungszweck: Anti-TEM8/ATR/ANTXR1 Antibody APC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TEM8/ATR/ANTXR1 recombinant protein (Position: E33-D301).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu ANTXR1

Target: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Andere Bezeichnung: ANTXR1

Hintergrund:

Background: Anthrax toxin receptor 1 (ANTXR1 or also known asTEM8) is a protein that in humans is encoded by the ANTXR1 gene. This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

Gene Full Name: ANTXR cell adhesion molecule 1

Gen-ID: 84168

UniProt: Q9H6X2