Ancient Ubiquitous Protein 1 Antikörper (AA 77-399) (Fluoro488)

Produktnummer ABIN7968390

Der Fluoro488-konjugierte Kaninchen Polyklonal anti-Ancient Ubiquitous Protein 1 Antikörper (ABIN7968390) detektiert spezifisch Ancient Ubiquitous Protein 1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Ancient Ubiquitous Protein 1 Antikörper (AA 77-399) (Fluoro488) (ABIN7968390)

Target: Ancient Ubiquitous Protein 1 (Aup1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ancient Ubiquitous Protein 1 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Ancient Ubiquitous Protein 1 Antikörper (Fluoro488)

Bindungsspezifität: AA 77-399

Verwendungszweck: Anti-AUP1 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human AUP1 recombinant protein (Position: A77-R399).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Ancient Ubiquitous Protein 1

Target: Ancient Ubiquitous Protein 1 (Aup1)

Andere Bezeichnung: AUP1

Hintergrund:

Background: Ancient ubiquitous protein 1 is a protein that in humans is encoded by the AUP1 gene. The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.

Gene Full Name: AUP1 lipid droplet regulating VLDL assembly factor

Gen-ID: 550

UniProt: Q9Y679