APRT Antikörper (C-Term) (Cy3)

Produktnummer ABIN7966596

Der Cy3-konjugierte Kaninchen Polyklonal anti-APRT Antikörper (ABIN7966596) detektiert spezifisch APRT in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für APRT Antikörper (C-Term) (Cy3) (ABIN7966596)

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APRT Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-APRT Antikörper (Cy3)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Aprt Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse APRT, which shares 86.4% and 95.5% amino acid (aa) sequence identity with human and rat APRT, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu APRT

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Andere Bezeichnung: Aprt

Hintergrund:

Background: Adenine phosphoribosyltransferase (APRTase) is anenzymeencoded by theAPRTgene, found inhumanson chromosome 16. It belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: adenine phosphoribosyl transferase

Gen-ID: 11821

UniProt: P08030

Pathways: Ribonucleoside Biosynthetic Process