Acetyl-CoA Carboxylase beta Antikörper (C-Term) (HRP)

Produktnummer ABIN7965468

Der HRP-konjugierte Kaninchen Polyklonal anti-Acetyl-CoA Carboxylase beta Antikörper (ABIN7965468) detektiert spezifisch Acetyl-CoA Carboxylase beta in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Acetyl-CoA Carboxylase beta Antikörper (C-Term) (HRP) (ABIN7965468)

Target: Acetyl-CoA Carboxylase beta (ACACB)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetyl-CoA Carboxylase beta Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Acetyl-CoA Carboxylase beta Antikörper (HRP)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Acetyl Coenzyme A Carboxylase/ACACB Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Acetyl Coenzyme A Carboxylase/ACACB, which shares 64.7% amino acid (aa) sequence identity with mouse Acetyl Coenzyme A Carboxylase/ACACB.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Acetyl-CoA Carboxylase beta

Target: Acetyl-CoA Carboxylase beta (ACACB)

Andere Bezeichnung: ACACB

Hintergrund:

Background: Acetyl-CoA carboxylase 2 also known as ACC-beta or ACC2 is an enzyme that in humans is encoded by the ACACB gene. It is mapped to 12q24.11. Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.

Gene Full Name: acetyl-CoA carboxylase beta

Gen-ID: 32

UniProt: O00763

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process