XRN1 Antikörper (AA 523-1198) (PE)

Produktnummer ABIN7965140

Der Kaninchen Polyklonal anti-XRN1 Antikörper wird verwendet zum Nachweis von XRN1 in Proben von Human und Maus. Er wurde validiert für FACS.

Kurzübersicht für XRN1 Antikörper (AA 523-1198) (PE) (ABIN7965140)

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRN1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-XRN1 Antikörper (PE)

Bindungsspezifität: AA 523-1198

Verwendungszweck: Anti-XRN1 Antibody PE Conjugated

Homologie: Human XRN1 shares 93.2% amino acid (aa) sequence identity with mouse XRN1.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human XRN1 recombinant protein (Position: K523-H1198). Human XRN1 shares 93.2% amino acid (aa) sequence identity with mouse XRN1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu XRN1

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Andere Bezeichnung: XRN1

Hintergrund:

Background: 5'-3' exoribonuclease 1 (Xrn1) is a protein that in humans is encoded by the XRN1 gene. This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts ly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.

Gene Full Name: 5'-3' exoribonuclease 1

Gen-ID: 54464

UniProt: Q8IZH2