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Vimentin Antikörper (pSer56)

Name: Vimentin Antikörper (pSer56)
SKU: ABIN746828
Price: 357.7 EUR
Availability: InStock

Der Kaninchen Polyklonal Anti-Vimentin-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, Vimentin in Proben von Human und Maus zu detektieren.

Produktnummer ABIN746828

Kurzübersicht für Vimentin Antikörper (pSer56) (ABIN746828)

Target

Alle Vimentin (VIM) Antikörper anzeigen

Vimentin (VIM)

Reaktivität

Human, Maus

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser Vimentin Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Discover our top product VIM Primärantikörper

Bindungsspezifität
34

32

17

16

12

10

8

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5

3

3

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2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

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1
pSer56

Kreuzreaktivität

Human, Maus

Homologie

Rat,Dog,Cow,Sheep,Pig,Guinea Pig

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human Vimentin around the phosphorylation site of Ser56

Isotyp

IgG
anti-Vimentin (VIM) (AA 371-466) antibody
VIM Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Affe WB, ELISA, FACS, IHC (p), ICC, IHC (fro), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-Vimentin (VIM) antibody
KO Validated VIM Reaktivität: Human WB, IHC, ELISA, IF, IHC (p), ICC, IP, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Vimentin (VIM) (AA 435-466), (C-Term) antibody
VIM Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Human, Maus, Ratte, Schwein, Huhn WB, IHC (p), ICC, IP Wirt: Maus Monoclonal VI-10 unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Säugetier WB, FACS, IHC (p), ICC Wirt: Maus Monoclonal VI-01 unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Human, Maus WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB41034 unconjugated

anti-Vimentin (VIM) (AA 1-200) antibody
VIM Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Human WB, IHC, IF Wirt: Maus Monoclonal C12 unconjugated

anti-Vimentin (VIM) (AA 430-457), (C-Term) antibody
VIM Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB16691 unconjugated

anti-Vimentin (VIM) antibody
KO Validated VIM Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Monoclonal unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Target

Vimentin (VIM)

Andere Bezeichnung

Vimentin

Hintergrund

Synonyms: FLJ36605, OTTHUMP00000019224, VIM, VIME_HUMAN, Vimentin.
Background: Vimentin is the major subunit protein of the intermediate filaments of mesenchymal cells. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain-dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis. Immunohistochemical staining for Vimentin is characteristic of sarcomas (of neural, muscle and fibroblast origin) compared with carcinomas which are generally negative. Melanomas, lymphomas and vascular tumors may all stain for Vimentin. Vimentin are thus of value in the differential diagnosis of undifferentiated neoplasms and malignant tumors. They are generally used with a panel of other including those recognizing cytokeratins, lymphoid markers, S100, desmin and neurofilaments.

Gen-ID

7431

Pathways

Caspase Kaskade in der Apoptose