TRIM37 Antikörper (C-Term)

Produktnummer ABIN7938530

Der Kaninchen Polyklonal anti-TRIM37 Antikörper wird verwendet zum Nachweis von TRIM37 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für TRIM37 Antikörper (C-Term) (ABIN7938530)

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM37 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRIM37 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TRIM37 antibody (pAb), sample

Aufreinigung: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of human TRIM37.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2,000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu TRIM37

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Andere Bezeichnung: TRIM37

Hintergrund:

Background_Plain: TRIM37 (Tripartite Motif Containing 37) is an E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).

Aliases: MUL, POB1, TEF3

Molekulargewicht: 120 kDa

NCBI Accession: NP_056109