POLR2F Antikörper (pThr4)

Produktnummer ABIN7938442

Dieser Ratte Monoklonal Antikörper detektiert spezifisch POLR2F in WB, IF, ELISA, ChIP, IP, ICC und DB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für POLR2F Antikörper (pThr4) (ABIN7938442)

Target: POLR2F (Polymerase (RNA) II (DNA Directed) Polypeptide F (POLR2F))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser POLR2F Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), Immunocytochemistry (ICC), Dot Blot (DB)

Klon: 6D7

Produktdetails anti-POLR2F Antikörper

Bindungsspezifität: pThr4

Verwendungszweck: RNA pol II CTD phospho Thr4 antibody (mAb) (Clone 6D7)

Aufreinigung: Protein G Chromatography

Immunogen: This antibody was raised against a synthetic peptide corresponding to RNA Pol II CTD phosphorylated at threonine 4.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB: 0.5 - 2 μg/mL DB: 1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu POLR2F

Target: POLR2F (Polymerase (RNA) II (DNA Directed) Polypeptide F (POLR2F))

Andere Bezeichnung: RNA pol II

Hintergrund:

Background_Plain: RNA pol II (RNA polymerase II) is a complex of 12 proteins that participates in transcription, mRNA processing, and transcription-coupled DNA repair. RNA polymerase II is distinguished by its large carboxyl-terminal repeat domain (CTD), composed of repeats of the consensus heptapeptide Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Polo-like kinase 3 (plk3) has been reported to phosphorylate Thr4 which may be required for transcriptional elongation.

Aliases: RPB1, RPO2, POLR2, POLRA, RPBh1, RPOL2, RpIILS, hsRPB1, hRPB220

Molekulargewicht: 240 kDa

NCBI Accession: NP_000928

Pathways: Regulatorische RNA Pathways