PHF6 Antikörper (N-Term)

Produktnummer ABIN7938407

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PHF6 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PHF6 Antikörper (N-Term) (ABIN7938407)

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PHF6 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PHF6 antibody (pAb)

Aufreinigung: Affinity Purified

Immunogen: This antibody was generated using a peptide from the N-terminal region of human PHF6 (PHD finger protein 6 isoform 1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB*: 1:500 - 1:1,000 dilution *Note: Many chromatin-bound proteins are not soluble in a low salt nuclear extract and fractionate to the pellet. Therefore, we recommend a High Salt / Sonication Protocol when preparing nuclear extracts for Western blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu PHF6

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Andere Bezeichnung: PHF6

Hintergrund:

Background_Plain: PHF6 is a member of the plant homeodomain finger (PHF) family, which has a potential rode in regulation of chromatin accessibility to lineage-specific transcription factors as part of the nucleosome remodeling and deacetylase (NuRD) epigenetic complex. PHF6 has been reported as a tumor suppressor in association with hematopoietic malignancies including T-cell acute lymphoblastic leukemia (T-ALL) and acute myeloid leukemia (AML). PHF6 may have tissue-specific expression, and is overexpressed in both breast and colorectal cancers. Germline mutations in PHF6 are the cause of the Börjeson-Forssman-Lehmann X-linked intellectual disability syndrome (BFLS).

Aliases: PHD Finger Protein 6, CENP-31

Molekulargewicht: 45 kDa

NCBI Accession: NP_115834