METTL16 Antikörper

Produktnummer ABIN7938344

Der Kaninchen Polyklonal anti-METTL16 Antikörper wird verwendet zum Nachweis von METTL16 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für METTL16 Antikörper (ABIN7938344)

Target: METTL16 (Methyltransferase Like 16 (METTL16))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser METTL16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-METTL16 Antikörper

Verwendungszweck: METTL16 antibody (pAb)

Aufreinigung: Protein A Chromatography

Immunogen: This METTL16 antibody was raised against a fusion protein corresponding to human METTL16.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 0.5 μg/mL-2 μg/mL For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.05 % Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu METTL16

Target: METTL16 (Methyltransferase Like 16 (METTL16))

Andere Bezeichnung: METTL16

Hintergrund:

Background_Plain: N6-methylated adenine (m6A) is prevalently present in nearly all RNA types and can be found in all organisms from bacteria to humans. It preferentially appears around stop codons and within long internal exons in mammalian messager RNAs. m6A plays an important role in the efficiency of mRNA splicing, processing, translation efficiency, editing and mRNA stability. m6A also occurs in other RNA molecules, such as primary miRNA (pri-miRNAs). METTL16 (Methyltransferase-Like Protein 16) is an RNA N6-methyltransferase that methylates adenosine residues of a subset of mRNAs and U6 smaller nuclear RNAs. METTL16 controls a significant portion of m6A epitranscriptome by regulating SAM homeostasis and plays a role in S-adenosyl-L-methionine homeostasis by regulating the expression of MAT2A transcripts.

Aliases: Methyltransferase-Like Protein 16

Molekulargewicht: 64.9 kDa

NCBI Accession: NP_076991