Histone H1 Antikörper (AA 109-256)

Produktnummer ABIN7938159

Der Maus Monoklonal anti-Histone H1 Antikörper (Klon 1G6-E3) (ABIN7938159) detektiert spezifisch Histone H1 in WB, IF, IP, ChIP und ChIP-seq. Dieser Antikörper reagiert spezifisch mit Proben aus Drosophila melanogaster.

Kurzübersicht für Histone H1 Antikörper (AA 109-256) (ABIN7938159)

Target: Histone H1

Reaktivität: Drosophila melanogaster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Histone H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Klon: 1G6-E3

Produktdetails anti-Histone H1 Antikörper

Bindungsspezifität: AA 109-256

Verwendungszweck: Histone H1 antibody (mAb) (Clone 1G6-E3), sample

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against a recombinant protein containing amino acids 109-256 of Drosophila melanogaster Histone H1. This region of the protein is not conserved in mammals, the antibody is not likely to cross-react to human, mouse or rat Histone H1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 0.2 - 1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu Histone H1

Target: Histone H1

Hintergrund:

Background_Plain: The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points. Histone H1 is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation and play a major role in regulating gene expression.

Aliases: 1G6-E3

Molekulargewicht: 35 kDa

NCBI Accession: NP_001027286