HIRA Antikörper

Produktnummer ABIN7938156

Der Maus Monoklonal anti-HIRA Antikörper (Klon WC119-2H11) (ABIN7938156) detektiert spezifisch HIRA in WB, IF und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für HIRA Antikörper (ABIN7938156)

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HIRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: WC119-2H11

Produktdetails anti-HIRA Antikörper

Verwendungszweck: HIRA antibody (mAb) (Clone WC119.2H11)

Aufreinigung: Protein G Chromatography

Immunogen: This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1 - 2 μg/mL dilution For optimal results, we recommend the addition of 0.05 % Tween-20 to all blocking solutions to reduce background in Western blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu HIRA

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Andere Bezeichnung: HIRA

Hintergrund:

Background_Plain: HIRA (DGCR1, TUP1) is a histone chaperone that preferentially places the variant Histone H3.3 in nucleosomes, replacing canonical Histone H3 during the cell cycle. HIRA is required for the periodic repression of histone gene transcription during the cell cycle and when complexed with ASF1a is involved in the formation of the senescence-associated heterochromatin foci.

Aliases: TUP1, DGCR1, TUPLE1

Molekulargewicht: 120 kDa

NCBI Accession: NP_003316

Pathways: Chromatin Binding