DPPA2 Antikörper

Produktnummer ABIN7938108

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DPPA2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für DPPA2 Antikörper (ABIN7938108)

Target: DPPA2 (Developmental Pluripotency Associated 2 (DPPA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPPA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DPPA2 Antikörper

Verwendungszweck: DPPA2 antibody (pAb)

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against a peptide corresponding to DPPA2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 0.5 μg/mL-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu DPPA2

Target: DPPA2 (Developmental Pluripotency Associated 2 (DPPA2))

Andere Bezeichnung: DPPA2

Hintergrund:

Background_Plain: DPPA2 and DPPA4 (developmental pluripotency associated 2 and 4) are small heterodimerizing nuclear proteins linked in the biological processes of transcription and transcription regulation. The encoded proteins have a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. The nuclear factor encoded by the gene is involved in the maintenance of pluripotency in stem cells and is found to be essential for embryogenesis. DPPA2 and DPPA4 are required to maintain H3K4me3 and H3K27me3 at important bivalent promoters depicted in pluripotent cells by low H3K4me3 levels and initiating but not elongating RNA polymerase II. This gene is thought to play an important role in tumor progression because when mutated it is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers.

Aliases: Developmental Pluripotency Associated 2

Molekulargewicht: 32 kDa

NCBI Accession: NP_620170

Pathways: Stem Cell Maintenance