BRD4 Antikörper (C-Term)

Produktnummer ABIN7938066

Der Kaninchen Polyklonal anti-BRD4 Antikörper wird verwendet zum Nachweis von BRD4 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für BRD4 Antikörper (C-Term) (ABIN7938066)

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BRD4 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: BRD4 antibody (pAb)

Aufreinigung: Protein A Chromatography

Immunogen: This BRD4 antibody was raised against a peptide within the C-terminal region of human BRD4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: *WB: 0.5 - 2.0 μg/mL dilution *For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.05 % Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified rabbit IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu BRD4

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Andere Bezeichnung: BRD4

Hintergrund:

Background_Plain: BRD4 (Bromodomain-containing protein 4, aka HUNK1) is a chromatin-associated protein with two bromo domains that binds acetylated histone H3 and H4. BRD4 is homologous to Xenopus MCAP, and like MCAP, BRD4 associates with chromosomes during mitosis, predominantly in the non-centromeric regions. A chromosomal aberration involving BRD4 (producing a BRD4-NUT fusion protein) is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. BRD4 is involved in the expression of extracellular matrix gene expression, and its misregulation may be involved in breast cancer progression.

Aliases: CAP, MCAP, HUNK1, HUNKI

Molekulargewicht: 180 kDa

NCBI Accession: NP_490597

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interaktom