SRF Antikörper (pSer103)

Produktnummer ABIN745898

Produktdetails anti-SRF Antikörper

Target: SRF (Serum Response Factor (SRF))

Bindungsspezifität: pSer103

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human SRF around the phosphorylation site of Ser103

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SRF Antikörper (ABIN745898)

Stern, Haverkamp, Sinske, Tedeschi, Naumann, Di Giovanni, Kochanek, Nordheim, Knöll: "The transcription factor serum response factor stimulates axon regeneration through cytoplasmic localization and cofilin interaction." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 48, pp. 18836-48, (2013) (PubMed).

Details zu SRF

Target: SRF (Serum Response Factor (SRF))

Andere Bezeichnung: SRF (SRF Produkte)

Synonyme: AW049942 antikoerper, AW240594 antikoerper, MCM1 antikoerper, SRFX antikoerper, XSRF antikoerper, srf-A antikoerper, RGD1559787 antikoerper, srf antikoerper, srf1 antikoerper, serum response factor antikoerper, serum response factor L homeolog antikoerper, serum response factor a antikoerper, Srf antikoerper, SRF antikoerper, srf.L antikoerper, srfa antikoerper

Hintergrund:

Synonyms: Serum Response Factor SRF phospho S103, SRF phospho Ser103, P-SRF Ser103, c fos serum response element binding factor, Serum Response Factor SRF, c fos serum response element binding transcription factor, ELK3, ERP, MCM 1, MCM-1, MCM1, OTTHUMP00000039820, SAP2, Serum response factor, SRF, SRF serum response factor c fos serum response element binding transcription factor, SRF_HUMAN.

Background: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008].

Gen-ID: 6722