INPPL1 Antikörper (pTyr1135) (Biotin)

Produktnummer ABIN745750

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch INPPL1 in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für INPPL1 Antikörper (pTyr1135) (Biotin) (ABIN745750)

Target: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INPPL1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-INPPL1 Antikörper (Biotin)

Bindungsspezifität: pTyr1135

Kreuzreaktivität: Human, Maus

Homologie: Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human SHIP2 around the phosphorylation site of Tyr1135

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu INPPL1

Target: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Andere Bezeichnung: INPPL1

Hintergrund:

Synonyms: 4, 5-trisphosphate 5-phosphatase 2, 51C protein, EC 3.1.3.n1, inositol polyphosphate phosphatase like 1, Inositol polyphosphate phosphatase like protein 1, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, INPPL1, Phosphatidylinositol 3, Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2, Protein 51C, SH2 domain containing inositol 5' phosphatase 2, SH2 domain-containing inositol 5''-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SHIP-2, SHIP2, SHIP2_HUMAN.

Background: The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.

Gen-ID: 3636

Pathways: Platelet-derived growth Factor Receptor Signaling