DLG2 Antikörper (pTyr340) (Cy7)

Produktnummer ABIN744989

Der Kaninchen Polyklonal Anti-DLG2-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, DLG2 in Proben von Ratte und Maus zu detektieren.

Kurzübersicht für DLG2 Antikörper (pTyr340) (Cy7) (ABIN744989)

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLG2 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-DLG2 Antikörper (Cy7)

Bindungsspezifität: pTyr340

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PSD93 around the phosphorylation site of Tyr340

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DLG2

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Andere Bezeichnung: PSD93

Hintergrund:

Synonyms: Channel associated protein of synapse 110, Channel associated protein of synapses 110kD, Channel-associated protein of synapse-110, Chapsyn 110, Chapsyn-110, Chapsyn110, discs large homolog 2, Discs, large homolog 2 Drosophila, Disks large homolog 2, DKFZp781D1854, DKFZp781E0954, Dlg 2, dlg2, DLG2_HUMAN, Dlgh 2, Dlgh2, FLJ37266, Gm1197, MGC131811, Postsynaptic density protein PSD 93, Postsynaptic density protein PSD-93, Postsynaptic density protein PSD93, PSD 93, PSD93.

Background: PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

Gen-ID: 1740