UTS2R Antikörper (2nd Cytoplasmic Loop)

Produktnummer ABIN7885632

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch UTS2R in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für UTS2R Antikörper (2nd Cytoplasmic Loop) (ABIN7885632)

Target: UTS2R (Urotensin 2 Receptor (UTS2R))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UTS2R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Güteklasse: Carrier-free

Produktdetails anti-UTS2R Antikörper

Bindungsspezifität: 2nd Cytoplasmic Loop, AA 154-167

Verwendungszweck: A Rabbit Ployclonal Antibody to Urotensin II Receptor

Homologie: Bovine - identical, human,canine - 13,14 amino acid residues identical

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: (C)RPLDTVQRSKGYRK, corresponding to amino acid residues 154-167 of rat URIIR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Kommentare:

Negative Control: (ABIN7237551)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW)

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu UTS2R

Target: UTS2R (Urotensin 2 Receptor (UTS2R))

Andere Bezeichnung: Urotensin 2 receptor

Hintergrund:

Synonyms: Urotensin 2 receptor, UR-II-R, UR2R, UTS2R, SENR, GPR14

Description: Urotensin II is a powerful vasoconstrictive substance. The human urotensin II receptor (UR-II-R) was originally isolated as an orphan receptor (GPR14) from neural and sensory tissues.1,2 Urotensin II is expressed in various human tissues such as the CNS, skeletal muscle, smooth muscle, pancreas, and heart.3-5 Binding of urotensin II to the receptor leads to activation of phospholipase C. The resulting increase in intracellular Ca2+ may cause the contraction of vascular smooth muscle. ERK1/2 phophorylation may also be involved in mediating the biological activities of urotensin II.6 Recently, evidence has accumulated indicating that urotensin II is also expressed in various kinds of tumor cells such as adrenal tumors and neuroblastomas. In those cells, urotensin II was reported to stimulate cell growth.7-9

Gen-ID: 57305

UniProt: P49684