GPR174 Antikörper (Extracellular Loop)

Produktnummer ABIN7884975

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GPR174 in WB, FACS und LCI. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für GPR174 Antikörper (Extracellular Loop) (ABIN7884975)

Target: GPR174 (G Protein-Coupled Receptor 174 (GPR174))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR174 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Live Cell Imaging (LCI)

Güteklasse: Carrier-free

Produktdetails anti-GPR174 Antikörper

Bindungsspezifität: AA 160-175, Extracellular Loop

Verwendungszweck: A Rabbit Polyclonal Antibody to GPR174

Homologie: Human - 15,16 amino acid residues identical, mouse,rat - 13

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: (C)DTSGNRTK(S)FVDLPTR, corresponding to amino acid residues 160 - 175 of human GPR174

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:400

FC: 5 μg per reaction

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Kommentare:

Negative Control: (ABIN7235384)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW)

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu GPR174

Target: GPR174 (G Protein-Coupled Receptor 174 (GPR174))

Andere Bezeichnung: G-protein coupled receptor 174

Hintergrund:

Synonyms: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79

Description: GPR174 (LysoPS, LYPSR3), is one of three lysophosphatidyl serine receptors, belonging to the superfamily of G-protein coupled receptors. Lysophospholipids are a diverse group of small, membrane-derived phospholipids that act as extracellular signals1.Activation of GPR174 leads to an increase in cAMP cellular levels, leading to cellular morphological changes, cell to cell adhesion, and delays in cell proliferation2.GPR174 is reported to be a genetic risk locus for Graves disease, an autoimmune disorder that causes hyperthyroidism3 and as a negative regulator of T-cells activation4.

Gen-ID: 84636

UniProt: Q9BXC1