Chloride Channel 5 Antikörper (Extracellular)

Produktnummer ABIN7884875

Der Kaninchen Polyklonal anti-Chloride Channel 5 Antikörper (ABIN7884875) detektiert spezifisch Chloride Channel 5 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte und Maus.

Kurzübersicht für Chloride Channel 5 Antikörper (Extracellular) (ABIN7884875)

Target: Chloride Channel 5 (CLCN5)

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Chloride Channel 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Güteklasse: Carrier-free

Produktdetails anti-Chloride Channel 5 Antikörper

Bindungsspezifität: AA 401-415, Extracellular

Verwendungszweck: A Rabbit Polyclonal Antibody to CLC-5 (CLCN5) Channel

Homologie: Mouse - identical, human - 14,15 amino acid residues identical

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: CDYENHFNTSKGGEL, corresponding to amino acid residues 401-415 of rat CLCN5 

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Kommentare:

Negative Control: (ABIN7235090)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW)

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu Chloride Channel 5

Target: Chloride Channel 5 (CLCN5)

Andere Bezeichnung: CLCN5

Hintergrund:

Synonyms: CLCN5, Chloride channel 5, Chloride transporter ClC-5, H+/Cl- exchange transporter 5, DENTS

Description: CLC5 is a member of the voltage-dependent Cl- channel family that includes nine known members. Based on sequence similarity, CLC5 is closely linked to the CLC3 and CLC4 subunits. CLC-5 is mainly found in intracellular vesicles, particularly in early endosomes, where it is believed to contribute to their acidification.The channel is mainly expressed in the kidney, although it has also been found in the small intestine, brain and liver.Mutations in the CLC5 gene cause Dent's disease, an X-linked renal disorder.

Gen-ID: 25749

UniProt: P51796