Aquaporin 7 Antikörper (Intracellular, N-Term)

Produktnummer ABIN7884771

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Aquaporin 7 in WB, IHC, IF und IC. Es zeigt Reaktivität gegenüber Proben von Ratte und Maus.

Kurzübersicht für Aquaporin 7 Antikörper (Intracellular, N-Term) (ABIN7884771)

Target: Aquaporin 7 (AQP7)

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aquaporin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)

Güteklasse: Carrier-free

Produktdetails anti-Aquaporin 7 Antikörper

Bindungsspezifität: AA 7-24, Intracellular, N-Term

Verwendungszweck: A Rabbit Polyclonal Antibody to Aquaporin 7 Channel

Homologie: 18 amino acid residues identical,Mouse - 15, human - 11

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: ENIQSVLQKTWVREFLAE, corresponding to amino acid residues 7-24 of rat AQP7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:500

FC: The optimal concentration should be determined by the user

ICC: 1:800

IHC: 1:100

IP: The optimal concentration should be determined by the user

Kommentare:

Negative Control: (ABIN7234775)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW)

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu Aquaporin 7

Target: Aquaporin 7 (AQP7)

Andere Bezeichnung: AQP7

Hintergrund:

Synonyms: AQP7, Aquaglyceroporin-7, AQPap, Aquaporin adipose

Description: Aquaporin 7 (AQP-7) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes. The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permeability characteristics: the aquaporins that are only permeated by water and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-7, AQP-3, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores.AQP-7 is expressed in ovary, testis, kidney and adipose tissue.The function of AQP-7 in adipose tissue attracted much interest as mice deficient in AQP-7 developed adult-onset obesity and Type 2 Diabetes. AQP-7 modulates adipocyte glycerol permeability thereby controlling triglyceride accumulation and fat cell size.

Gen-ID: 29171

UniProt: P56403