Aquaporin 5 Antikörper (C-Term, Intracellular)

Produktnummer ABIN7884769

Der Kaninchen Polyklonal anti-Aquaporin 5 Antikörper wird verwendet zum Nachweis von Aquaporin 5 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, IF und IC.

Kurzübersicht für Aquaporin 5 Antikörper (C-Term, Intracellular) (ABIN7884769)

Target: Aquaporin 5 (AQP5)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aquaporin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)

Güteklasse: Carrier-free

Produktdetails anti-Aquaporin 5 Antikörper

Bindungsspezifität: AA 251-265, C-Term, Intracellular

Verwendungszweck: A Rabbit Polyclonal Antibody to Aquaporin 5 Channel

Homologie: Mouse - identical, human - 10,16 amino acid residues identical

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: (C)DHREERKKTIELTAH corresponding to amino acid residues 251-265 of rat AQP5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Kommentare:

Negative Control: (ABIN7234767)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.2 mL double distilled water (DDW)

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu Aquaporin 5

Target: Aquaporin 5 (AQP5)

Andere Bezeichnung: AQP5

Hintergrund:

Synonyms: AQP5

Description: The importance of the aquaporin water channels was underscored by awarding the 2003 Nobel Prize in Chemistry to Peter Agre "for the discovery of water channels". Today, eleven mammalian proteins that belong to the aquaporin family have been identified. The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. Aquaporin 5 (AQP5) is expressed in secretory glands, lung and eye, where it works in modulating the rate of fluid release. Since a number of pathological conditions including pulmonary edema, respiratory distress syndrome and congestive heart failure are characterized by disrupted fluid transport, it has been suggested that modulation of the expression of AQP5 could be a novel modality of treatment of the above illnesses. Indeed, several studies have shown that AQP5 expression is downregulated in animal models of acute lung infection.

Gen-ID: 25241

UniProt: P47864