Substance P Antikörper

Produktnummer ABIN7884251

Der Ratte Monoklonal anti-Substance P Antikörper (Klon NC1-34) (ABIN7884251) detektiert spezifisch Substance P in IHC, ELISA und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Crab und Taube.

Kurzübersicht für Substance P Antikörper (ABIN7884251)

Target: Substance P

Reaktivität: Human, Crab, Taube

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Substance P Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Klon: NC1-34

Produktdetails anti-Substance P Antikörper

Verwendungszweck: Substance P Rat Monoclonal Antibody (NC1/34)

Spezifität: This antibody recognizes the COOH-terminal end of substance P. It does not recognize Leu- or Met enkephalin, somatostatin or beta-endorphin, cross-reactivity with eledoisin: 5 % . It recognizes Substance P in post-mortem tissue of the human brain.

Homologie: All Mammals

Immunogen: Substance P

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: IHC and ICC 1:200,ICC 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: If reconstituted with deionized water in 0.5 mL: IHC and ICC 1:200 - 1:500. Optimal dilution has to be determined by the user.

Buffer: Lyophilized tissue culture supernatant

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Haltbarkeit: 24 months

Details zu Substance P

Target: Substance P

Hintergrund:

Substance P, tachykinin, neuropeptide, neurokinin, SP, anti-tachykinin, anti-neuropeptide, anti-neurokinin, anti-SP

The discovery of substance P (SP) was reported in 1931. After more than 70 years of investigation, SP is perhaps the best understood neuropeptide transmitter. Substance P is an undecapeptide, which by the mid-1980s was recognized to belong to the tachykinin peptide family, it is also member of the neurokinins. It has been proposed that SP, released from primary afferent nerve endings, plays a role in chronic inflammation and pain. Neurotransmitters appear to play a key role in the regulation of emotions and antagonists of their receptors may be novel psychotropic drugs of the future.