UGT1A10 Antikörper

Produktnummer ABIN7882635

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch UGT1A10 in WB und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für UGT1A10 Antikörper (ABIN7882635)

Target: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGT1A10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-UGT1A10 Antikörper

Verwendungszweck: UDP-glucuronosyltransferase 1A10 Antibody / UGT1A10

Sequenz: HIVHLEDHLF CQYLFRNALE IASEILQ

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids HIVHLEDHLFCQYLFRNALEIASEILQ were used as the immunogen for the UDP-glucuronosyltransferase 1A10 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the UDP-glucuronosyltransferase 1A10 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the UDP-glucuronosyltransferase 1A10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu UGT1A10

Target: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Andere Bezeichnung: UDP-glucuronosyltransferase 1A10

Hintergrund: UDP-glucuronosyltransferase 1-10 is an enzyme that in humans is encoded by the UGT1A10 gene. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.

UniProt: Q9HAW8

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha