Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Tumor Protein p73 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.
TP73
Reaktivität: Human
WB, IHC, IF, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal dilution of the p73 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store the p73 antibody at -20oC.
Target
Tumor Protein p73 (TP73)
(Tumor Protein P73 (TP73))
Andere Bezeichnung
p73
Hintergrund
The TP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [RefSeq]