Synaptophysin Antikörper

Produktnummer ABIN7882406

Der Maus Monoklonal anti-Synaptophysin Antikörper (Klon 3G12) (ABIN7882406) detektiert spezifisch Synaptophysin in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte und Maus.

Kurzübersicht für Synaptophysin Antikörper (ABIN7882406)

Target: Synaptophysin (SYP)

Reaktivität: Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Synaptophysin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 3G12

Produktdetails anti-Synaptophysin Antikörper

Verwendungszweck: Synaptophysin Antibody / SYP

Sequenz: MLLLADMDVV NQLVAGGQFR VVKEPL

Aufreinigung: Affinity purified

Immunogen: Amino acids MLLLADMDVVNQLVAGGQFRVVKEPL from the human protein were used as the immunogen for the Synaptophysin antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Synaptophysin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Synaptophysin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Synaptophysin

Target: Synaptophysin (SYP)

Andere Bezeichnung: Synaptophysin

Hintergrund: SYP (Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22). The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38 kDa. It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity